Cholesterol 24-hydroxylase-IN-1

Modify Date: 2024-01-21 14:45:42

Cholesterol 24-hydroxylase-IN-1 Structure
Cholesterol 24-hydroxylase-IN-1 structure
Common Name Cholesterol 24-hydroxylase-IN-1
CAS Number 1613480-70-8 Molecular Weight 313.40
Density N/A Boiling Point N/A
Molecular Formula C17H23N5O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cholesterol 24-hydroxylase-IN-1


Cholesterol 24-hydroxylase-IN-1 (compound 17) is a potent, orally active, and highly selective cholesterol 24-hydroxylase (CH24H or CYP46A1) inhibitor (IC50=8.5 nM). Cholesterol 24-hydroxylase-IN-1 can cross blood-brain barrier[1].

 Names

Name Cholesterol 24-hydroxylase-IN-1

 Cholesterol 24-hydroxylase-IN-1 Biological Activity

Description Cholesterol 24-hydroxylase-IN-1 (compound 17) is a potent, orally active, and highly selective cholesterol 24-hydroxylase (CH24H or CYP46A1) inhibitor (IC50=8.5 nM). Cholesterol 24-hydroxylase-IN-1 can cross blood-brain barrier[1].
Related Catalog
References

[1]. Kajita Y, et al. Discovery of Novel 3-Piperidinyl Pyridine Derivatives as Highly Potent and Selective Cholesterol 24-Hydroxylase (CH24H) Inhibitors. J Med Chem. 2022;65(4):3343-3358.

 Chemical & Physical Properties

Molecular Formula C17H23N5O
Molecular Weight 313.40
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