2304750-84-1

2304750-84-1 structure

Name: CXCR4 antagonist 8
Chemical Name: CXCR4 antagonist 8
CAS Number: 2304750-84-1
Molecular Formula: C₂₁H₂₆N₆
Molecular Weight: 362.47
Catalog: Signaling Pathways GPCR/G Protein CXCR
Create Date: 2022-08-12 10:43:33
Modify Date: 2024-01-11 17:50:52
CXCR4 antagonist 8 (Compound 3) is a CXCR4 antagonist with an IC50 of 57 nM. CXCR4 antagonist 8 inhibits CXCL12 induced cytosolic calcium increase with an IC50 of 0.24 nM. CXCR4 antagonist 8 inhibits CXLC12/CXCR4 mediated cell migration[1].

Name	CXCR4 antagonist 8

Description	CXCR4 antagonist 8 (Compound 3) is a CXCR4 antagonist with an IC50 of 57 nM. CXCR4 antagonist 8 inhibits CXCL12 induced cytosolic calcium increase with an IC50 of 0.24 nM. CXCR4 antagonist 8 inhibits CXLC12/CXCR4 mediated cell migration[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> GPCR/G Protein >> CXCR Signaling Pathways >> Immunology/Inflammation >> CXCR
Target	CXCR4:57 nM (IC50)
References	[1]. Lin Y, et al. Design, synthesis, and evaluation of novel CXCR4 antagonists based on an aminoquinoline template. Bioorg Chem. 2020 Jun;99:103824.

Molecular Formula	C₂₁H₂₆N₆
Molecular Weight	362.47