2304750-83-0

2304750-83-0 structure

2304750-83-0 structure

Name: CXCR4 antagonist 9
Chemical Name: CXCR4 antagonist 9
CAS Number: 2304750-83-0
Molecular Formula: C₂₁H₂₇FN₆
Molecular Weight: 382.48
Catalog: Signaling Pathways GPCR/G Protein CXCR
Create Date: 2022-08-13 05:04:43
Modify Date: 2024-01-08 20:38:36
CXCR4 antagonist 9 (Compound 2) is a CXCR4 antagonist with an IC50 of 15 nM. CXCR4 antagonist 9 inhibits CXCL12 induced cytosolic calcium increase with an IC50 of 1.3 nM[1].

Name	CXCR4 antagonist 9

Description	CXCR4 antagonist 9 (Compound 2) is a CXCR4 antagonist with an IC50 of 15 nM. CXCR4 antagonist 9 inhibits CXCL12 induced cytosolic calcium increase with an IC50 of 1.3 nM[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> GPCR/G Protein >> CXCR Signaling Pathways >> Immunology/Inflammation >> CXCR
Target	CXCR4:15 nM (IC50)
References	[1]. Lin Y, et al. Design, synthesis, and evaluation of novel CXCR4 antagonists based on an aminoquinoline template. Bioorg Chem. 2020 Jun;99:103824.

Molecular Formula	C₂₁H₂₇FN₆
Molecular Weight	382.48