2414629-82-4

2414629-82-4 structure

2414629-82-4 structure

Name: hCAIX/XII-IN-2
Chemical Name: hCAIX/XII-IN-2
CAS Number: 2414629-82-4
Molecular Formula: C₁₉H₁₄N₂O₄
Molecular Weight: 334.33
Catalog: Signaling Pathways Metabolic Enzyme/Protease Carbonic Anhydrase
Create Date: 2022-08-03 16:44:52
Modify Date: 2024-01-09 19:12:49
hCAIX/XII-IN-2 (compound 6a) is a potent and selective hCAIX and hCAXIIinhibitor with Ki values of >10000, >10000, 30.0, 3.6 nM for hCAI, hCAII, hCAIX and hCAXII, respectively[1].

Name	hCAIX/XII-IN-2

Description	hCAIX/XII-IN-2 (compound 6a) is a potent and selective hCAIX and hCAXIIinhibitor with Ki values of >10000, >10000, 30.0, 3.6 nM for hCAI, hCAII, hCAIX and hCAXII, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase
Target	Ki: >10000 nM (hCAI); >10000 nM (hCAII); 30.0 nM (hCAIX); 3.6 nM (hCAXII)[1].
References	[1]. Thacker PS, et al. Design, synthesis and biological evaluation of coumarin linked 1,2,4-oxadiazoles as selective carbonic anhydrase IX and XII inhibitors. Bioorg Chem. 2020 May;98:103739.

Molecular Formula	C₁₉H₁₄N₂O₄
Molecular Weight	334.33