2389034-45-9

2389034-45-9 structure

2389034-45-9 structure

Name: HCAIX-IN-2
Chemical Name: HCAIX-IN-2
CAS Number: 2389034-45-9
Molecular Formula: C₁₉H₁₆N₈O₄S
Molecular Weight: 452.45
Catalog: Signaling Pathways Metabolic Enzyme/Protease Carbonic Anhydrase
Create Date: 2022-11-01 17:18:13
Modify Date: 2024-04-06 12:21:12
HCAIX-IN-2 (compound 9d) is a selective carbonic anhydrase inhibitor with the Ki values of 24.6 nM and 45.3 nM for hCA IX and hCA XII, respectively[1].

Name	HCAIX-IN-2

Description	HCAIX-IN-2 (compound 9d) is a selective carbonic anhydrase inhibitor with the Ki values of 24.6 nM and 45.3 nM for hCA IX and hCA XII, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase
Target	CA I:2481 nM (Ki) hCA II:456.2 nM (Ki) hCA IX:24.6 nM (Ki) hCA XII:45.3 nM (Ki)
References	[1]. Mohamed A Said, et al. Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole-based benzenesulfonamides as novel carbonic anhydrase inhibitors. Eur J Med Chem. 2020 Jan 1;185:111843.

Molecular Formula	C₁₉H₁₆N₈O₄S
Molecular Weight	452.45