2490468-39-6

2490468-39-6 structure

2490468-39-6 structure

Name: HSV-1/HSV-2-IN-2
Chemical Name: HSV-1/HSV-2-IN-2
CAS Number: 2490468-39-6
Molecular Formula: C₁₇H₁₄ClFN₄OS
Molecular Weight: 376.84
Catalog: Signaling Pathways Anti-infection HSV
Create Date: 2022-08-17 14:08:51
Modify Date: 2024-03-05 11:01:37
HSV-1/HSV-2-IN-2 is a HSV-1, HSV-2 and VV inhibitor with EC50 values of 6.8, 8.9 and 8.9 µM, respectively. HSV-1/HSV-2-IN-2 shows antiviral activity[1].

Name	HSV-1/HSV-2-IN-2

Description	HSV-1/HSV-2-IN-2 is a HSV-1, HSV-2 and VV inhibitor with EC50 values of 6.8, 8.9 and 8.9 µM, respectively. HSV-1/HSV-2-IN-2 shows antiviral activity[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HSV Research Areas >> Infection
Target	HSV-1:6.8 μM (EC50) HSV-2:8.9 μM (EC50)
In Vitro	HSV-1/HSV-2-IN-2(100 µM, 3-6Days, HEL cell cultures) is effective and nontoxic against HSV-1 (KOS), HSV-2 (G), HSV-1 TK- KOS ACVr and VV at low μM doses[1]. Cell Viability Assay Cell Line: HEL cell cultures Concentration: 100 µM Incubation Time: 3-6 Days Result: Showed nontoxic and effective at 6.8, 8.9, 6.8 and 8.9 µM against HSV-1 (KOS), HSV-2 (G), HSV-1 TK- KOS ACVr and VV, respectively.
References	[1]. Dizhong Chen et al. Synthesis and biological evaluation of 6-phenylpurine linked hydroxamates as novel histone deacetylase inhibitors. Bioorg Chem. 2020 May;98:103724.

Molecular Formula	C₁₇H₁₄ClFN₄OS
Molecular Weight	376.84