HSV-1/HSV-2-IN-2

Modify Date: 2024-03-05 11:01:37

HSV-1/HSV-2-IN-2 Structure
HSV-1/HSV-2-IN-2 structure
Common Name HSV-1/HSV-2-IN-2
CAS Number 2490468-39-6 Molecular Weight 376.84
Density N/A Boiling Point N/A
Molecular Formula C17H14ClFN4OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HSV-1/HSV-2-IN-2


HSV-1/HSV-2-IN-2 is a HSV-1, HSV-2 and VV inhibitor with EC50 values of 6.8, 8.9 and 8.9 µM, respectively. HSV-1/HSV-2-IN-2 shows antiviral activity[1].

 Names

Name HSV-1/HSV-2-IN-2

 HSV-1/HSV-2-IN-2 Biological Activity

Description HSV-1/HSV-2-IN-2 is a HSV-1, HSV-2 and VV inhibitor with EC50 values of 6.8, 8.9 and 8.9 µM, respectively. HSV-1/HSV-2-IN-2 shows antiviral activity[1].
Related Catalog
Target

HSV-1:6.8 μM (EC50)

HSV-2:8.9 μM (EC50)

In Vitro HSV-1/HSV-2-IN-2(100 µM, 3-6Days, HEL cell cultures) is effective and nontoxic against HSV-1 (KOS), HSV-2 (G), HSV-1 TK- KOS ACVr and VV at low μM doses[1]. Cell Viability Assay Cell Line: HEL cell cultures Concentration: 100 µM Incubation Time: 3-6 Days Result: Showed nontoxic and effective at 6.8, 8.9, 6.8 and 8.9 µM against HSV-1 (KOS), HSV-2 (G), HSV-1 TK- KOS ACVr and VV, respectively.
References

[1]. Dizhong Chen et al. Synthesis and biological evaluation of 6-phenylpurine linked hydroxamates as novel histone deacetylase inhibitors. Bioorg Chem. 2020 May;98:103724.

 Chemical & Physical Properties

Molecular Formula C17H14ClFN4OS
Molecular Weight 376.84