2641601-67-2

2641601-67-2 structure

Name: PROTAC EZH2 Degrader-1
Chemical Name: PROTAC EZH2 Degrader-1
CAS Number: 2641601-67-2
Molecular Formula: C₅₄H₆₇N₇O₈
Molecular Weight: 942.15
Catalog: Signaling Pathways Epigenetics Histone Methyltransferase
Create Date: 2022-08-10 09:33:47
Modify Date: 2024-01-08 11:38:32
PROTAC EZH2 Degrader-1 (Compound 150d), a potent PROTAC EZH2 Degrader, exerts inhibitory effect on EZH2 methyltransferase activity with the IC50 of 2.7 nM. EZH2 plays an important role in many tumorigenesis and development processes[1].

Name	PROTAC EZH2 Degrader-1

Description	PROTAC EZH2 Degrader-1 (Compound 150d), a potent PROTAC EZH2 Degrader, exerts inhibitory effect on EZH2 methyltransferase activity with the IC50 of 2.7 nM. EZH2 plays an important role in many tumorigenesis and development processes[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Methyltransferase Signaling Pathways >> PROTAC >> PROTAC
Target	EZH2:2.7 nM (IC50)
References	[1]. Juan Xia, et al. Targeting Enhancer of Zeste Homolog 2 for the Treatment of Hematological Malignancies and Solid Tumors: Candidate Structure-Activity Relationships Insights and Evolution Prospects. J Med Chem. 2022 May 26;65(10):7016-7043.

Molecular Formula	C₅₄H₆₇N₇O₈
Molecular Weight	942.15