2771297-34-6

2771297-34-6 structure

2771297-34-6 structure

Name: CYP3A4-IN-1
Chemical Name: CYP3A4-IN-1
CAS Number: 2771297-34-6
Molecular Formula: C₃₁H₃₇N₅O₃S
Molecular Weight: 559.72
Catalog: Signaling Pathways Metabolic Enzyme/Protease Cytochrome P450
Create Date: 2022-09-04 09:49:35
Modify Date: 2024-09-13 07:53:02
CYP3A4-IN-1 (compound 5a) is a potent cytochrome P450 3A4 (CYP3A4) inhibitor with an IC50 value of 0.085 µM[1].

Name	CYP3A4-IN-1

Description	CYP3A4-IN-1 (compound 5a) is a potent cytochrome P450 3A4 (CYP3A4) inhibitor with an IC50 value of 0.085 µM[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450
Target	CYP3A4:0.085 μM (IC50)
References	[1]. Samuels ER, et al. An increase in side-group hydrophobicity largely improves the potency of ritonavir-like inhibitors of CYP3A4. Bioorg Med Chem. 2020 Mar 15;28(6):115349.

Molecular Formula	C₃₁H₃₇N₅O₃S
Molecular Weight	559.72