691869-12-2
691869-12-2 structure
- Name: EP4 receptor antagonist 4
- Chemical Name: EP4 receptor antagonist 4
- CAS Number: 691869-12-2
- Molecular Formula: C19H14N2OS
- Molecular Weight: 318.39
- Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
- Create Date: 2022-10-06 14:59:18
- Modify Date: 2024-09-18 08:19:05
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EP4 receptor antagonist 4 is an EP4 receptor agonist with the human pEC50 value of 6.3[1].
| Name | EP4 receptor antagonist 4 |
|---|
| Description | EP4 receptor antagonist 4 is an EP4 receptor agonist with the human pEC50 value of 6.3[1]. |
|---|---|
| Related Catalog | |
| Target |
EP4:6.3 (pEC50) |
| In Vitro | EP4 receptor antagonist 4 (24 h) treatment shows agonism in HEK293 cells stably transfected with hEP4[1]. EP4 receptor antagonist 4 (30 min) treatment shows agonism (pEC50<5) and antagonism (pIC50<5)[1]. Cell Viability Assay[1] Cell Line: HEK293 cells Concentration: Incubation Time: 24 hours Result: Exhibited the human pEC50 value of 6.3. |
| References |
[1]. Joannes Theodorus Maria Linders, et al. Bicyclic derivatives as ep4 agonists. WO2008092860A1 |
| Molecular Formula | C19H14N2OS |
|---|---|
| Molecular Weight | 318.39 |