2038858-11-4

2038858-11-4 structure

2038858-11-4 structure

Name: SARS-CoV-2 nsp3-IN-2
Chemical Name: SARS-CoV-2 nsp3-IN-2
CAS Number: 2038858-11-4
Molecular Formula: C₁₀H₁₂N₄O₂
Molecular Weight: 220.23
Catalog: Research Areas Infection
Create Date: 2022-11-13 17:37:46
Modify Date: 2024-01-12 07:10:35
SARS-CoV-2 nsp3-IN-2 is a macrodomain (Mac1) inhibitor with IC50 value of 180 μM. SARS-CoV-2 nsp3-IN-2 is a small molecule chemical probe and can be used for the research of viral[1].

Name	SARS-CoV-2 nsp3-IN-2

Description	SARS-CoV-2 nsp3-IN-2 is a macrodomain (Mac1) inhibitor with IC50 value of 180 μM. SARS-CoV-2 nsp3-IN-2 is a small molecule chemical probe and can be used for the research of viral[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
Target	IC50: 180 μM (Mac1)[1]
In Vitro	SARS-CoV-2 nsp3-IN-2 emonstrates weak potency against Mac1 in an ADP-ribose binding AlphaScreen assay with IC50 value of 180 μM[1].
References	[1]. Lavinia M Sherrill, et al. Design, Synthesis and Evaluation of Inhibitors of the SARS-CoV2 nsp3 Macrodomain. bioRxiv. 2022 Feb 28;2022.02.27.482176.

Molecular Formula	C₁₀H₁₂N₄O₂
Molecular Weight	220.23