2769040-91-5
2769040-91-5 structure
- Name: NLRP3-IN-11
- Chemical Name: NLRP3-IN-11
- CAS Number: 2769040-91-5
- Molecular Formula: C17H17ClN4O2
- Molecular Weight: 344.80
- Catalog: Signaling Pathways Immunology/Inflammation NOD-like Receptor (NLR)
- Create Date: 2022-11-06 19:31:32
- Modify Date: 2024-04-07 18:36:26
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NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC50 value of ＜0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases[1].
| Name | NLRP3-IN-11 |
|---|
| Description | NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC50 value of ＜0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases[1]. |
|---|---|
| Related Catalog | |
| Target |
NLRP3:<0.3 μM (IC50) |
| In Vitro | NLRP3-IN-11 has biological activity with an IC50 value of ＜0.3 μM in human PBMC NLRP3 assay[1] |
| References |
[1]. HY-W048205, et al. Compounds for inhibiting NLRP3 and uses thereof. Patent. US11319319B1. |
| Molecular Formula | C17H17ClN4O2 |
|---|---|
| Molecular Weight | 344.80 |