1704638-35-6

1704638-35-6 structure

Name: NLRP3-IN-13
Chemical Name: NLRP3-IN-13
CAS Number: 1704638-35-6
Molecular Formula: C₁₉H₁₅N₃O₃S
Molecular Weight: 365.41
Catalog: Signaling Pathways Immunology/Inflammation NOD-like Receptor (NLR)
Create Date: 2023-04-20 10:49:17
Modify Date: 2024-04-08 10:02:20
NLRP3-IN-13 (Compound C77 in reference patent) is a selective and potent NLRP3 inhibitor (IC50: 2.1 μM). NLRP3-IN-13 inhibits NLRP3 andNLRC4 inflammasomes, and inhibits NLRP3-mediated IL-1β production. NLRP3-IN-13 also inhibits NLRP3 ATPase activity. NLRP3-IN-13 can be used in the research of neuroinflammatory disorders[1].

Name	NLRP3-IN-13

Description	NLRP3-IN-13 (Compound C77 in reference patent) is a selective and potent NLRP3 inhibitor (IC50: 2.1 μM). NLRP3-IN-13 inhibits NLRP3 andNLRC4 inflammasomes, and inhibits NLRP3-mediated IL-1β production. NLRP3-IN-13 also inhibits NLRP3 ATPase activity. NLRP3-IN-13 can be used in the research of neuroinflammatory disorders[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> NOD-like Receptor (NLR) Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
Target	NLRP3
References	[1]. Devita Robert, et al. Benzoxazolones as inhibitors of inflammasomes and their preparation. Patent. WO2022187804.

Molecular Formula	C₁₉H₁₅N₃O₃S
Molecular Weight	365.41