NLRP3-IN-13

Modify Date: 2024-04-08 10:02:20

NLRP3-IN-13 structure	Common Name	NLRP3-IN-13
	CAS Number	1704638-35-6	Molecular Weight	365.41
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₁₅N₃O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of NLRP3-IN-13

NLRP3-IN-13 (Compound C77 in reference patent) is a selective and potent NLRP3 inhibitor (IC50: 2.1 μM). NLRP3-IN-13 inhibits NLRP3 andNLRC4 inflammasomes, and inhibits NLRP3-mediated IL-1β production. NLRP3-IN-13 also inhibits NLRP3 ATPase activity. NLRP3-IN-13 can be used in the research of neuroinflammatory disorders[1].

Name	NLRP3-IN-13

Description	NLRP3-IN-13 (Compound C77 in reference patent) is a selective and potent NLRP3 inhibitor (IC50: 2.1 μM). NLRP3-IN-13 inhibits NLRP3 andNLRC4 inflammasomes, and inhibits NLRP3-mediated IL-1β production. NLRP3-IN-13 also inhibits NLRP3 ATPase activity. NLRP3-IN-13 can be used in the research of neuroinflammatory disorders[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> NOD-like Receptor (NLR) Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
Target	NLRP3
References	[1]. Devita Robert, et al. Benzoxazolones as inhibitors of inflammasomes and their preparation. Patent. WO2022187804.

Molecular Formula	C₁₉H₁₅N₃O₃S
Molecular Weight	365.41

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: NLRP3-IN-13
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Purity: 99.0%
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NLRP3-IN-13

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