370096-57-4
370096-57-4 structure
- Name: ROS kinases-IN-1
- Chemical Name: WAY-602746
- CAS Number: 370096-57-4
- Molecular Formula: C20H16N4O
- Molecular Weight: 328.373
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK ROS
- Create Date: 2022-12-14 08:35:23
- Modify Date: 2024-04-04 00:01:01
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ROS kinases-IN-1 (pag 98) is a ROS tyrosine kinase inhibitor with IC50 value of 1.22 μM. ROS kinases-IN-1 shows anti-tumor activity[1].
| Name | WAY-602746 |
|---|
| Description | ROS kinases-IN-1 (pag 98) is a ROS tyrosine kinase inhibitor with IC50 value of 1.22 μM. ROS kinases-IN-1 shows anti-tumor activity[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 1.22 μM (ROS kinase)[1] |
| In Vitro | ROS kinases-IN-1 (1-100 μM; 1 d) inhibits the growth of cervical cancer cell and glioblastoma cells[1]. Cell Viability Assay[1] Cell Line: HeLa, U138, U87, LN18, and U118 cells Concentration: 1, 10, and 100 μM Incubation Time: one day Result: Showed EC50s for HeLa, U138, U87, LN18, and U118 cells of 20, 8, 8, 12, and 7 μM, respectively. |
| References |
| Molecular Formula | C20H16N4O |
|---|---|
| Molecular Weight | 328.373 |