2499537-22-1

2499537-22-1 structure

2499537-22-1 structure

Name: DENV-IN-7
Chemical Name: DENV-IN-7
CAS Number: 2499537-22-1
Molecular Formula: C₂₄H₂₂O₈
Molecular Weight: 438.43
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2023-01-26 12:24:27
Modify Date: 2024-04-07 19:00:22
DENV-IN-7, a flavone analog, is a dengue virus (DENV) inhibitor with an EC50 value of 70 nM. DENV-IN-7 has low toxicity against normal cell and anti-dengue activity[1].

Name	DENV-IN-7

Description	DENV-IN-7, a flavone analog, is a dengue virus (DENV) inhibitor with an EC50 value of 70 nM. DENV-IN-7 has low toxicity against normal cell and anti-dengue activity[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis
In Vitro	DENV-IN-7 (compound 5d; 10 μM; 48 h) 对 LLC/MK2 细胞具有低毒性[1]。 DENV-IN-7 (1 nM-10 μM; 72 h) 具有抗登革热活性，并抑制 DENV2 感染的 LLC/MK2 细胞中的病毒复制[1]。 Cell Viability Assay[1] Cell Line: LLC/MK2 cells Concentration: 10 μM Incubation Time: 48 hours Result: Had non-toxic with the viability above 75%.
References	[1]. Patigo A, et, al. Design, synthesis, in vitro, in silico, and SAR studies of flavone analogs towards anti-dengue activity. Sci Rep. 2022 Dec 14;12(1):21646.

Molecular Formula	C₂₄H₂₂O₈
Molecular Weight	438.43