Name | CB2R/FAAH modulator-3 |
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Description | CB2R/FAAH modulator-3 (compound 27) is a dual targeting modulator that acts as a CB2R agonist and FAAH inhibitor. The Ki values for CB2R/FAAH modulator-3 are 20.1 and 67.6 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 3.4 μM. CB2R/FAAH modulator-3 can be used in studies related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection[1]. |
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Related Catalog | |
Target |
CB1:67.6 nM (Ki) CB2:20.1 nM (Ki) |
In Vitro | CB2R/FAAH modulator-3 (compound 27)(10 μM) 在未刺激的单核细胞和巨噬细胞中,可以降低促炎细胞因子 TNFα、IFN-γ、IL-1β 和 IL6 的产生[1]。 |
References |
Molecular Formula | C22H31NO2 |
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Molecular Weight | 341.49 |