142276-31-1

142276-31-1 structure

Name: Cidofovir diphosphate
Chemical Name: Cidofovir diphosphate
CAS Number: 142276-31-1
Molecular Formula: C₈H₁₆N₃O₁₂P₃
Molecular Weight: 439.15
Catalog: Research Areas Infection
Create Date: 2023-06-15 17:52:52
Modify Date: 2024-01-08 20:58:02
Cidofovir diphosphate is an active intracellular metabolite of Cidofovir. Cidofovir diphosphate is a selective inhibitor of viral DNA polymerases with Ki values of 6.6, 0.86 and 1.4 μM for HCMV, HSV-1 and HSV-2 DNA polymerase, respectively[1][2].

Name	Cidofovir diphosphate

Description	Cidofovir diphosphate is an active intracellular metabolite of Cidofovir. Cidofovir diphosphate is a selective inhibitor of viral DNA polymerases with Ki values of 6.6, 0.86 and 1.4 μM for HCMV, HSV-1 and HSV-2 DNA polymerase, respectively[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
Target	Viral DNA polymerase[1]
References	[1]. Hitchcock MJM, et al. Cidofovir, a New Agent with Potent Anti-Herpesvirus Activity. 1996. [2]. Magee WC, et al. Mechanism of inhibition of vaccinia virus DNA polymerase by cidofovir diphosphate. Antimicrob Agents Chemother. 2005 Aug;49(8):3153-62.

Molecular Formula	C₈H₁₆N₃O₁₂P₃
Molecular Weight	439.15