957-77-7
957-77-7 structure
- Name: 5-Hydroxyuridine
- Chemical Name: 5-hydroxyuridine
- CAS Number: 957-77-7
- Molecular Formula: C9H12N2O7
- Molecular Weight: 260.20
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2018-05-28 08:00:00
- Modify Date: 2024-01-10 18:43:32
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5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | 5-hydroxyuridine |
|---|---|
| Synonyms |
5-Hydroxy-uridin
5-Hydroxy-uracil-ribotid Uridine, 5-hydroxy- Uridine,5-hydroxy 5-hydroxy-uridine 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-5-hydroxy-pyrimidine-2,4-quinone 5-Hydroxyuridine 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxy-pyrimidine-2,4-dione |
| Description | 5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.8±0.1 g/cm3 |
|---|---|
| Molecular Formula | C9H12N2O7 |
| Molecular Weight | 260.20 |
| Exact Mass | 260.064453 |
| PSA | 145.01000 |
| LogP | -1.51 |
| Index of Refraction | 1.698 |
| Storage condition | 2-8°C |
