129198-88-5

129198-88-5 structure
129198-88-5 structure
  • Name: Autocamtide-2
  • Chemical Name: Autocamtide 2 trifluoroacetate salt
  • CAS Number: 129198-88-5
  • Molecular Formula: C65H118N22O20
  • Molecular Weight: 1527.77000
  • Catalog: Peptides
  • Create Date: 2018-12-25 14:46:59
  • Modify Date: 2024-01-02 22:12:28
  • Autocamtide 2 is a highly selective peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). It can be used in the CaMKII activity assay.

Name Autocamtide 2 trifluoroacetate salt
Synonyms autocamtide-2
Autocamtide 2
Description Autocamtide 2 is a highly selective peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). It can be used in the CaMKII activity assay.
Related Catalog
In Vitro The Ca/calmodulin dependent protein kinases (CaMKs) are multifunctional serine/threonine kinases whose activity are regulated through Ca2+ signaling. It is multifunctional best known for its critical role in learning and memory. Recent studies demonstrates that high levels of different isoform of CaMK, especially for CaMKII, expresses in several cancers such as lung, breast, prostate and colon cancer. CaMKII phosphorylates nearly 40 different proteins, including enzymes, ion channels, kinases, and transcription factors and plays a critical role in the regulation of proliferation, differentiation and survival of various cancer cells[1].
References

[1]. Wang YY, et al. The emerging role of CaMKII in cancer. Oncotarget. 2015 May 20;6(14):11725-34.

Molecular Formula C65H118N22O20
Molecular Weight 1527.77000
Exact Mass 1526.89000
PSA 726.28000
LogP 2.64810
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport