87691-91-6
87691-91-6 structure
- Name: Tiospirone
- Chemical Name: 8-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-8-azaspiro[4.5]decane-7,9-dione
- CAS Number: 87691-91-6
- Molecular Formula: C24H32N4O2S
- Molecular Weight: 440.60100
- Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
- Create Date: 2018-08-24 19:43:50
- Modify Date: 2024-01-06 14:48:53
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Tiospirone is a 5-HT2 receptor antagonist with affinity for D2, 5-HT1a, and 5-HT7, and sigma receptors. Tiospirone decreases consumption of ethanol while increasing food intake of rats. Tiospirone can also reduce the reinforcing properties of Cocaine exhibited in the conditioned place preference paradigm[1][2].
| Name | 8-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-8-azaspiro[4.5]decane-7,9-dione |
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| Synonyms |
Tiospirona [Spanish]
tiaspirone Tiospirone [INN] Tiospironum [Latin] [14C]-Tiospirone Tiospironum Tiospirona 8-{4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl}-8-azaspiro[4.5]decane-7,9-dione 8-Azaspiro(4,5)decane-7,9-dione,8-(4-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)butyl) TIOSPIRONE |
| Description | Tiospirone is a 5-HT2 receptor antagonist with affinity for D2, 5-HT1a, and 5-HT7, and sigma receptors. Tiospirone decreases consumption of ethanol while increasing food intake of rats. Tiospirone can also reduce the reinforcing properties of Cocaine exhibited in the conditioned place preference paradigm[1][2]. |
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| Related Catalog | |
| References |
| Density | 1.29g/cm3 |
|---|---|
| Boiling Point | 600.9ºC at 760 mmHg |
| Molecular Formula | C24H32N4O2S |
| Molecular Weight | 440.60100 |
| Flash Point | 317.2ºC |
| Exact Mass | 440.22500 |
| PSA | 84.99000 |
| LogP | 3.84870 |
| Index of Refraction | 1.652 |
| Precursor 10 | |
|---|---|
| DownStream 0 | |