215312-86-0
215312-86-0 structure
- Name: Sulfo-EMCS
- Chemical Name: sodium,1-[6-(2,5-dioxopyrrol-1-yl)hexanoyloxy]-2,5-dioxopyrrolidine-3-sulfonate
- CAS Number: 215312-86-0
- Molecular Formula: C14H15N2NaO9S
- Molecular Weight: 410.33
- Create Date: 2016-07-29 13:09:55
- Modify Date: 2024-01-08 12:16:37
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6-Maleimidocaproic acid sulfo-NHS (Sulfo-EMCS) sodium is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | sodium,1-[6-(2,5-dioxopyrrol-1-yl)hexanoyloxy]-2,5-dioxopyrrolidine-3-sulfonate |
|---|---|
| Synonyms |
sodium 1-[6-(2,5-dioxopyrrol-1-yl)hexanoyloxy]-2,5-dioxopyrrolidine-3-sulfonate
sulfo-EMCS sodium salt Sulfo-EMCS 6-Maleimidocaproic Acid Sulfo-N-Succinimidyl Ester 1-[[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]oxy]-2,5-dioxo-3-pyrrolidinesulfonic Acid Sodium Salt |
| Description | 6-Maleimidocaproic acid sulfo-NHS (Sulfo-EMCS) sodium is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1] |
| References |
| Melting Point | 158-165 °C |
|---|---|
| Molecular Formula | C14H15N2NaO9S |
| Molecular Weight | 410.33 |
| Exact Mass | 410.04000 |
| PSA | 166.64000 |
| Storage condition | 2-8℃ |
| Hazard Codes | Xi |
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