Name | 5,7-dihydroxychromen-4-one |
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Synonyms |
4H-1-Benzopyran-4-one, 5,7-dihydroxy-
5,7-dihydroxy-4H-1-benzopyran-4-one 5,7-Dihydroxychromone 2H-1-Benzopyran-2-one, 5,7-dihydroxy- 5,7-Dihydroxy-4H-chromen-4-one 5,7-Dihydroxy-2H-chromen-2-one 5,7-dihydroxy-chromen-4-one 5,7-Dihydroxy-chromen-4-on 5,7-DIHYDROXYCOUMARIN |
Description | 5,7-Dihydroxychromone, the extract of Cudrania tricuspidata, activates Nrf2/ARE signal and exerts neuroprotective effects against 6-hydroxydopamine (6-OHDA)-induced oxidative stress and apoptosis. 5,7-Dihydroxychromone inhibits the expression of activated caspase-3 and caspase-9 and cleaved PARP in 6-OHDA-induced SH-SY5Y cells[1]. |
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Related Catalog | |
Target |
Nrf2 Caspase-3 Caspase-9 PARP |
References |
Density | 1.6±0.1 g/cm3 |
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Boiling Point | 399.4±42.0 °C at 760 mmHg |
Melting Point | 232-273℃ |
Molecular Formula | C9H6O4 |
Molecular Weight | 178.141 |
Flash Point | 170.8±21.4 °C |
Exact Mass | 178.026611 |
PSA | 70.67000 |
LogP | 0.54 |
Vapour Pressure | 0.0±1.0 mmHg at 25°C |
Index of Refraction | 1.689 |
Hazard Codes | Xi |
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HS Code | 2914400090 |
~5% 31721-94-5 |
Literature: Li, Su-Yi; Wang, Xiao-Bing; Xie, Sai-Sai; Jiang, Neng; Wang, Kelvin D.G.; Yao, He-Quan; Sun, Hong-Bin; Kong, Ling-Yi European Journal of Medicinal Chemistry, 2013 , vol. 69, p. 632 - 646 |
~93% 31721-94-5 |
Literature: Zheng, Shu-Yan; Li, Xiao-Ping; Tan, Hong-Sheng; Yu, Chun-Hui; Zhang, Jing-Hua; Shen, Zheng-Wu European Journal of Organic Chemistry, 2013 , # 7 p. 1356 - 1366 |
~% 31721-94-5 |
Literature: Jain, A. C.; Gupta, S. M.; Tyagi, O. D. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 11 p. 1036 - 1039 |
~% 31721-94-5 |
Literature: Organic Preparations and Procedures International, , vol. 23, # 3 p. 390 - 392 |
~% 31721-94-5 |
Literature: Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 28, # 5 p. 497 - 502 Khimiya Geterotsiklicheskikh Soedinenii, Sbornik, , # 5 p. 595 - 600 |
~% 31721-94-5 |
Literature: Jain, A. C.; Gupta, S. M.; Tyagi, O. D. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 11 p. 1036 - 1039 |
~% 31721-94-5 |
Literature: Organic Preparations and Procedures International, , vol. 23, # 3 p. 390 - 392 |
Precursor 7 | |
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DownStream 3 | |
HS Code | 2914400090 |
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Summary | 2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |