531-44-2

531-44-2 structure

Name: scopolin
Chemical Name: scopolin
CAS Number: 531-44-2
Molecular Formula: C₁₆H₁₈O₉
Molecular Weight: 354.309
Catalog: Natural product Coumarin
Create Date: 2018-04-29 08:00:00
Modify Date: 2024-01-02 22:09:18
Scopolin is a coumarin isolated from Arabidopsis thaliana (Arabidopsis) roots[1]. Scopolin attenuated hepatic steatosis through activation of SIRT1-mediated signaling cascades[2].

Name	scopolin
Synonyms	Scopolin 2H-1-Benzopyran-2-one, 7-(β-D-glucopyranosyloxy)-6-methoxy- Scopoletin glucoside 7-(β-D-glucopyranosoyloxy)-6-methoxy-2H-1-benzopyran-2-one 2H-1-Benzopyran-2-one, 7- (β-D-glucopyranosyloxy)-6-methoxy- 5Mg 7-(b-D-Glucopyranosyloxy)-6-methoxy-2H-1-benzopyran-2-one Scopoletin 7-O-Glucoside 6-Methoxy-2-oxo-2H-chromen-7-yl β-D-glucopyranoside 2'-β-D-glucosyl scopolin Murrayin Scopolin (8CI) CPD-678 Scopoletin 7-glucoside 7β-D-Glucopyranosyloxy-6-methoxycoumarin Scopoline Scopoloside

Description	Scopolin is a coumarin isolated from Arabidopsis thaliana (Arabidopsis) roots[1]. Scopolin attenuated hepatic steatosis through activation of SIRT1-mediated signaling cascades[2].
Related Catalog	Signaling Pathways >> Epigenetics >> Sirtuin Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin Research Areas >> Metabolic Disease
Target	SIRT1
References	[1]. Siwinska J, et al. Identification of QTLs affecting scopolin and scopoletin biosynthesis in Arabidopsisthaliana. BMC Plant Biol. 2014 Oct 18;14:280. [2]. Yoo A, et al. Scopolin ameliorates high-fat diet induced hepatic steatosis in mice: potential involvement of SIRT1-mediated signaling cascades in the liver. Sci Rep. 2017 May 22;7(1):2251.

85011-57-0

1135-24-6

531-44-2

Literature: Chemistry of Natural Compounds, , vol. 18, # 6 p. 654 - 657 Khimiya Prirodnykh Soedinenii, , vol. 18, # 6 p. 691 - 695

98296-08-3

73-34-7

531-44-2

Literature: Chemistry of Natural Compounds, , vol. 16, # 2 p. 125 - 128 Khimiya Prirodnykh Soedinenii, , vol. 16, # 2 p. 168 - 172

92-61-5

5328-37-0

531-44-2

Literature: Angewandte Chemie - International Edition, , vol. 45, # 21 p. 3534 - 3538

1207857-19-9

531-44-2

Literature: Song, Shuang; Li, Yixiu; Feng, Ziming; Jiang, Jianshuang; Zhang, Peicheng Journal of Natural Products, 2010 , vol. 73, # 2 p. 177 - 184