BioBioPha
China
Product Name: trans-4-Hydroxycinnamic acid
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Purity: 98.0%
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: trans-4-Hydroxycinnamic acid
Price: ￥98.0/5g ￥298.0/25g ￥238.0/20mg
Purity: 98.0%
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DC Chemicals Limited
China
Product Name: 4-Hydroxycinnamic acid
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-Hydroxycinnamic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

501-98-4

501-98-4 structure

Name: trans-4-Hydroxycinnamic acid
Chemical Name: p-Coumaric acid
CAS Number: 501-98-4
Molecular Formula: C₉H₈O₃
Molecular Weight: 164.158
Catalog: Chemical pesticide Insecticide Rodenticide intermediate
Create Date: 2018-07-05 10:59:30
Modify Date: 2024-01-02 23:22:52
p-Coumaric acid is the abundant isomer of cinnamic acid which has antitumor and anti-mutagenic activities.

Name	p-Coumaric acid
Synonyms	4-Hydroxy cinnamic acid (2E)-3-(4-Hydroxyphenyl)acrylic acid trans-p-Cumaric Acid EINECS 231-000-0 3-(4-Hydroxy-phenyl)-acrylic acid trans-p-Coumaric Acid 2-propenoic acid, 3-(4-hydroxyphenyl)- E-4-Hydroxycinnamic Acid (E)-3-(4-Hydroxyphenyl)acrylic acid 2-Propenoic acid, 3-(4-hydroxyphenyl)-, (2E)- 4-Coumaric acid trans-4-Hydroxycinnamic Acid p-Hydroxycinnamic acid,predominantly trans MFCD00004399 4-Hydroxycinnamic acid

Description	p-Coumaric acid is the abundant isomer of cinnamic acid which has antitumor and anti-mutagenic activities.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cancer Natural Products >> Phenylpropanoids
References	[1]. Jaganathan SK, et al. Events associated with apoptotic effect of p-Coumaric acid in HCT-15 colon cancer cells. World J Gastroenterol. 2013 Nov 21;19(43):7726-34.

Density	1.3±0.1 g/cm3
Boiling Point	346.1±17.0 °C at 760 mmHg
Melting Point	214ºC
Molecular Formula	C₉H₈O₃
Molecular Weight	164.158
Flash Point	177.3±17.4 °C
Exact Mass	164.047348
PSA	57.53000
LogP	1.88
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.660
Water Solubility	soluble

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GD9095000

CHEMICAL NAME :: Cinnamic acid, p-hydroxy-, (E)-

CAS REGISTRY NUMBER :: 501-98-4

BEILSTEIN REFERENCE NO. :: 2207381

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H8-O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2850 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: GNRIDX Gendai no Rinsho. (Tokyo, Japan) V.1-10, 1967-76(?). Volume(issue)/page/year: 3,675,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1160 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: GNRIDX Gendai no Rinsho. (Tokyo, Japan) V.1-10, 1967-76(?). Volume(issue)/page/year: 3,675,1969

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S26-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	GD9095000
HS Code	2918290000

1392307-47-9

57-48-7

50-99-7

501-98-4

Literature: Nakamura, Seikou; Fujimoto, Katsuyoshi; Matsumoto, Takahiro; Nakashima, Souichi; Ohta, Tomoe; Ogawa, Keiko; Matsuda, Hisashi; Yoshikawa, Masayuki Phytochemistry, 2013 , vol. 92, p. 128 - 136

7400-08-0

~32%

501-98-4

Literature: Ueda, Minoru; Sawai, Yoshiyuki; Shibazaki, Yuichiro; Tashiro, Chitose; Ohnuki, Takashi; Yamamura, Shosuke Bioscience, Biotechnology and Biochemistry, 1998 , vol. 62, # 11 p. 2133 - 2137

3943-97-3

501-98-4

Literature: Pirrung, Michael C.; Chen, Jrlung; Rowley, Elizabeth G.; McPhail, Andrew T. Journal of the American Chemical Society, 1993 , vol. 115, # 16 p. 7103 - 7110

1225064-68-5

501-98-4

Literature: Morikawa, Toshio; Pan, Yingni; Ninomiya, Kiyofumi; Imura, Katsuya; Matsuda, Hisashi; Yoshikawa, Masayuki; Yuan, Dan; Muraoka, Osamu Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 5 p. 1882 - 1890

1899-30-5

501-98-4

7400-08-0

Literature: Regos, Ionela; Urbanella, Andrea; Treutter, Dieter Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 13 p. 5843 - 5852

87099-71-6

501-98-4

7400-08-0

Literature: Regos, Ionela; Urbanella, Andrea; Treutter, Dieter Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 13 p. 5843 - 5852

1108200-72-1

501-98-4

7400-08-0

Literature: Regos, Ionela; Urbanella, Andrea; Treutter, Dieter Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 13 p. 5843 - 5852

117405-49-9

50-99-7

501-98-4

7400-08-0

Literature: Regos, Ionela; Urbanella, Andrea; Treutter, Dieter Journal of Agricultural and Food Chemistry, 2009 , vol. 57, # 13 p. 5843 - 5852

Precursor 7
1392307-47-9 7400-08-0 3943-97-3 1225064-68-5
1899-30-5 87099-71-6 1108200-72-1
DownStream 1
123-07-9

HS Code	2918290000
Summary	HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

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