Name | 4-[(2-methylpropan-2-yl)oxycarbonylamino]butyl 4-methylbenzenesulfonate |
---|---|
Synonyms | Toluene-4-sulfonic acid 4-tert-butoxy-carbonylamino-butyl ester |
Description | Tos-O-C4-NH-Boc is an alkyl ether-based PROTAC linker can be used in the synthesis of PROTACs, such as BSJ-03-204 (HY-136250)[1]. |
---|---|
Related Catalog | |
Target |
Alkyl/ether |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Molecular Formula | C16H25NO5S |
---|---|
Molecular Weight | 343.43800 |
Exact Mass | 343.14500 |
PSA | 93.57000 |
LogP | 4.29040 |