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  • Product Name: CYCLOARTENOL
  • Price: ￥3400.0/5mg
  • Purity: 98.0%
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469-38-5 85955-30-2
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469-38-5

469-38-5 structure
469-38-5 structure
  • Name: CYCLOARTENOL
  • Chemical Name: cycloartenol
  • CAS Number: 469-38-5
  • Molecular Formula: C30H50O
  • Molecular Weight: 426.71700
  • Catalog: Signaling Pathways Apoptosis Apoptosis
  • Create Date: 2018-08-19 10:34:16
  • Modify Date: 2024-01-02 17:00:19
  • Cycloartenol, a phytosterol compound, is one of the key precusor substances for biosynthesis of numerous sterol compounds. Cycloartenol inhibits the migration of glioma cells and suppresses the phosphorylation of the p38 MAP kinase. Cycloartenol has a variety of pharmacological activities such as anti-inflammatory, anti-tumor, antioxidant, antibiosis and anti-alzheimer's disease. Cycloartenol also plays an important role in the process of plant growth and development[1][2].
Name cycloartenol
Synonyms CYCLOARTENOL
9,19-Cyclolanost-24-en-3-ol
9,19-CYCLO-9BETA-LANOST-24-EN-3BETA-OL
Description Cycloartenol, a phytosterol compound, is one of the key precusor substances for biosynthesis of numerous sterol compounds. Cycloartenol inhibits the migration of glioma cells and suppresses the phosphorylation of the p38 MAP kinase. Cycloartenol has a variety of pharmacological activities such as anti-inflammatory, anti-tumor, antioxidant, antibiosis and anti-alzheimer's disease. Cycloartenol also plays an important role in the process of plant growth and development[1][2].
Related Catalog
In Vitro Cycloartenol inhibits the proliferation and the colony formation potential of the glioma U87 cells in a concentration-dependent manner. The antiproliferative effects are found to be due to induction of Sub-G1 cell cycle arrest and triggering of apoptosis. Cycloartenol also causes significant alteration in the expression of Bax and Bcl-2[2].
References

[1]. Niu H, et al. Cycloartenol exerts anti-proliferative effects on Glioma U87 cells via induction of cell cycle arrest and p38 MAPK-mediated apoptosis. J BUON. 2018 Nov-Dec;23(6):1840-1845.

[2]. Zhang ZL, et al. [Research advance of functional plant pharmaceutical cycloartenol about pharmacological and physiological activity]. Zhongguo Zhong Yao Za Zhi. 2017 Feb;42(3):433-437.
Density 1.01 g/cm3
Boiling Point 505.5ºC at 760 mmHg
Melting Point 115-117ºC
Molecular Formula C30H50O
Molecular Weight 426.71700
Flash Point 221.9ºC
Exact Mass 426.38600
PSA 20.23000
LogP 8.16890
Vapour Pressure 2.47E-12mmHg at 25°C
Index of Refraction 1.538
Hazard Codes Xi: Irritant;
Safety Phrases 22-24/25
67-56-1 structure

67-56-1

21238-33-5 structure

21238-33-5

~%

1449-09-8 structure

1449-09-8

469-38-5 structure

469-38-5

Literature: MORINAGA MILK INDUSTRY CO., LTD. Patent: EP1882472 A1, 2008 ; Location in patent: Page/Page column 14 ;
21238-33-5 structure

21238-33-5

~93%

469-38-5 structure

469-38-5

Literature: Yoshida, Kumi; Hirose, Yoshihiko; Imai, Yutaka; Kondo, Tadao Agricultural and Biological Chemistry, 1989 , vol. 53, # 7 p. 1901 - 1912
14050-42-1 structure

14050-42-1

~%

514-45-4 structure

514-45-4

469-38-5 structure

469-38-5

79-63-0 structure

79-63-0

Literature: Hart, Elizabeth A.; Hua, Ling; Darr, Lisa B.; Wilson, William K.; Pang, Jihai; Matsuda, Seiichi P. T. Journal of the American Chemical Society, 1999 , vol. 121, # 42 p. 9887 - 9888
54910-48-4 structure

54910-48-4

~%

514-45-4 structure

514-45-4

469-38-5 structure

469-38-5

79-63-0 structure

79-63-0

Literature: Lodeiro, Silvia; Schulz-Gasch, Tanja; Matsuda, Seiichi P. T. Journal of the American Chemical Society, 2005 , vol. 127, # 41 p. 14132 - 14133
1259-10-5 structure

1259-10-5

~%

469-38-5 structure

469-38-5

Literature: Seo, Shujiro; Uomori, Atsuko; Yoshimura, Yohko; Takeda, Ken'ichi; Seto, Haruo; et.al. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 2407 - 2414
14050-42-1 structure

14050-42-1

~%

469-38-5 structure

469-38-5

Literature: Matsuda; Darr; Hart; Herrera; McCann; Meyer; Pang; Schepmann Organic letters, 2000 , vol. 2, # 15 p. 2261 - 2263
136891-87-7 structure

136891-87-7

~%

469-38-5 structure

469-38-5

Literature: Majumder; Ghosal Journal of the Indian Chemical Society, 1991 , vol. 68, # 2 p. 88 - 91

Chemsrc provides CAS#:469-38-5 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 469-38-5 | Chemsrc address: https://www.chemsrc.com/en/baike/588476.html

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