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  • China
  • Product Name: SCH-28080
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


76081-98-6

76081-98-6 structure
76081-98-6 structure
  • Name: SCH 28080
  • Chemical Name: 2-(2-methyl-8-phenylmethoxyimidazo[1,2-a]pyridin-3-yl)acetonitrile
  • CAS Number: 76081-98-6
  • Molecular Formula: C17H15N3O
  • Molecular Weight: 277.32
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel Proton Pump
  • Create Date: 2016-07-06 12:18:39
  • Modify Date: 2024-01-09 19:35:24
  • SCH28080 inhibits gastric H+/K+-ATPase by K+-competitive binding, with an IC50 value of 20 nM in rabbit microsomal membranes[1]. Antisecretory and cytoprotective activities[2].

Name 2-(2-methyl-8-phenylmethoxyimidazo[1,2-a]pyridin-3-yl)acetonitrile
Synonyms MFCD00834620
Description SCH28080 inhibits gastric H+/K+-ATPase by K+-competitive binding, with an IC50 value of 20 nM in rabbit microsomal membranes[1]. Antisecretory and cytoprotective activities[2].
Related Catalog
Target

IC50: 20 nM (H+/K+-ATPase, rabbit microsomal membranes)[1]

References

[1]. Scott CK, et al. Studies on the mechanism of action of the gastric microsomal (H+ + K+)-ATPase inhibitors SCH 32651 and SCH 28080. Biochem Pharmacol. 1987 Jan 1;36(1):97-104.

[2]. Long JF, et al. Gastric antisecretory and cytoprotective activities of SCH 28080. J Pharmacol Exp Ther. 1983 Jul;226(1):114-20.

Density 1.16g/cm3
Molecular Formula C17H15N3O
Molecular Weight 277.32
Exact Mass 277.12200
PSA 50.32000
LogP 3.28778
Index of Refraction 1.615
Storage condition -20°C
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases 22-24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933990090
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%