Name | 2-(2-methyl-8-phenylmethoxyimidazo[1,2-a]pyridin-3-yl)acetonitrile |
---|---|
Synonyms | MFCD00834620 |
Description | SCH28080 inhibits gastric H+/K+-ATPase by K+-competitive binding, with an IC50 value of 20 nM in rabbit microsomal membranes[1]. Antisecretory and cytoprotective activities[2]. |
---|---|
Related Catalog | |
Target |
IC50: 20 nM (H+/K+-ATPase, rabbit microsomal membranes)[1] |
References |
Density | 1.16g/cm3 |
---|---|
Molecular Formula | C17H15N3O |
Molecular Weight | 277.32 |
Exact Mass | 277.12200 |
PSA | 50.32000 |
LogP | 3.28778 |
Index of Refraction | 1.615 |
Storage condition | -20°C |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
---|---|
Safety Phrases | 22-24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2933990090 |
~% 76081-98-6 |
Literature: Kaminski, James J.; Bristol, James A.; Puchalski, Chester; Lovey, Raymond G.; Elliott, Arthur J.; et al. Journal of Medicinal Chemistry, 1985 , vol. 28, # 7 p. 876 - 892 |
~% 76081-98-6 |
Literature: Schering Corporation Patent: US4450164 A1, 1984 ; |
~% 76081-98-6 |
Literature: Schering Corporation Patent: US4450164 A1, 1984 ; |
~67% 76081-98-6 |
Literature: Kaminski, James J.; Bristol, James A.; Puchalski, Chester; Lovey, Raymond G.; Elliott, Arthur J.; et al. Journal of Medicinal Chemistry, 1985 , vol. 28, # 7 p. 876 - 892 |
~% 76081-98-6 |
Literature: Kaminski, James J.; Bristol, James A.; Puchalski, Chester; Lovey, Raymond G.; Elliott, Arthur J.; et al. Journal of Medicinal Chemistry, 1985 , vol. 28, # 7 p. 876 - 892 |
Precursor 7 | |
---|---|
DownStream 1 | |
HS Code | 2933990090 |
---|---|
Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |