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756526-06-4

756526-06-4 structure
756526-06-4 structure

Name amino-dPEG8.(TM).-t-butyl ester
Synonyms H2N-PEG8-CH2CH2COOtBu
H2N-PEG8- CH2CH2COOtBu
Description Amino-PEG8-Boc is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Hans-Georg Lerchen, et al. Antibody drug conjugates (adcs) and antibody prodrug conjugates (apdcs) with enzymatically cleavable groups. WO2016207089A1.

Molecular Formula C23H47NO10
Molecular Weight 497.62000
Exact Mass 497.32000
PSA 126.16000
LogP 1.51000
Hazard Codes Xn