66246-88-6
66246-88-6 structure
- Name: penconazole
- Chemical Name: penconazole
- CAS Number: 66246-88-6
- Molecular Formula: C13H15Cl2N3
- Molecular Weight: 284.184
- Catalog: Chemical pesticide Fungicide Other fungicides
- Create Date: 2018-08-20 16:37:50
- Modify Date: 2024-01-03 11:22:54
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Penconazole is a typical triazole fungicide, and mainly applied on apples, grapes, and vegetables to control powdery mildew. Penconazole inhibits sterol biosynthesis in fungi. Penconazole decrease AChE activity in the cerebrum and cerebellum of rats[1][2].
| Name | penconazole |
|---|---|
| Synonyms |
topasmz
(RS)-1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole EINECS 266-275-6 PENCONAZOL T5NN DNJ A1Y3&R BG DG 1-[2-(2,4-Dichlorophenyl)pentyl]-1H-1,2,4-triazole onmex MFCD00078737 1-[2-(2,4-Dichlorophenyl)-n-pentyl]-1H-1,2,4-triazole Topas 1-(2,4-Dichloro-β-propylphenethyl)-1H-1,2,4-triazole topaze 1H-1,2,4-Triazole, 1-[2-(2,4-dichlorophenyl)pentyl]- topazec penconazole topasc Pine gel rac-1-[(2R)-2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole |
| Description | Penconazole is a typical triazole fungicide, and mainly applied on apples, grapes, and vegetables to control powdery mildew. Penconazole inhibits sterol biosynthesis in fungi. Penconazole decrease AChE activity in the cerebrum and cerebellum of rats[1][2]. |
|---|---|
| Related Catalog | |
| In Vivo | Penconazole (67 mg/kg; i.p.; every 2 days during 9 days) induces oxidative stress in rat cerebrum and cerebellum tissues[2]. Penconazole has the ability to induce oxidative damage in the brain of adult rats, as evidenced by an increase of lipid peroxidation and protein oxidation, in addition to the perturbations in the enzymatic and nonenzymatic antioxidant status. Penconazole also affects the cholinergic system, activities of membrane-bound ATPases, and brain histoarchitecture. Penconazole is a potential neurotoxicant pesticide that exerts its neurotoxic effects via the generation of oxidative stress. Penconazole causes a significant inhibition of AChE activity in the cerebrum (11%) and cerebellum (25%) of adult rats[2]. Animal Model: Twelve male Wistar rats[2] Dosage: 67 mg/kg Administration: I.p.; every 2 days during 9 days Result: A significant increase was obtained in the absolute and relative weights of the cerebrum and cerebellum, respectively. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 415.3±55.0 °C at 760 mmHg |
| Melting Point | 57.6-60.3ºC |
| Molecular Formula | C13H15Cl2N3 |
| Molecular Weight | 284.184 |
| Flash Point | 204.9±31.5 °C |
| Exact Mass | 283.064301 |
| PSA | 30.71000 |
| LogP | 3.66 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.602 |
| Storage condition | 0-6°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Symbol |
GHS07, GHS08, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H361d-H410 |
| Precautionary Statements | P201-P273-P301 + P312 + P330-P308 + P313-P391-P501 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
| Hazard Codes | Xi |
| Safety Phrases | S22-S24/25 |
| RIDADR | UN 3077 9 / PGIII |
| RTECS | XZ4615000 |
| HS Code | 2933990015 |
|
~%
66246-88-6 |
| Literature: US4556717 A1, ; |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| HS Code | 2933990016 |
|---|---|
| Summary | 2933990016 1-(2-(2,4-dichlorophenyl)pentyl)-1h-1,2,4-triazole。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0% |