Name | 4-methoxyfuro[2,3-b]quinoline |
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Synonyms |
4-methoxyfuro[2,3-b]quinoline
Dictamine Dictamnine Furo[2,3-b]quinoline, 4-methoxy- 4-Methoxy-furo[2,3-b]quinoline |
Description | Dictamnine (Dictamine) has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma cells; A natural plant product has been reported to have antimicrobial activity against bacteria and fungi.IC50 value:Target: Dictamnine has antimicrobial activities against the model fungus Saccharomyces cerevisiae, with a minimum inhibitory concentration (MIC) value of 64 microg/ml [1]. Dic induced S phase cell cycle arrest at low concentration and cell apoptosis at high concentration in which loss of mitochondrial membrane potential (Δψmm) was not involved. In addition, inhibition of caspase-3 using the specific inhibitor, z-DQMD-fmk, did not attenuate Dic-induced apoptosis, implying that Dic-induced caspase-3-independent apoptosis [2]. |
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Related Catalog | |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 343.2±22.0 °C at 760 mmHg |
Melting Point | 133.5ºC |
Molecular Formula | C12H9NO2 |
Molecular Weight | 199.205 |
Flash Point | 161.4±22.3 °C |
Exact Mass | 199.063324 |
PSA | 35.26000 |
LogP | 2.94 |
Vapour Pressure | 0.0±0.7 mmHg at 25°C |
Index of Refraction | 1.672 |
Storage condition | -20℃ |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA
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Hazard Codes | N |
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Precursor 10 | |
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DownStream 7 | |