Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 5'-Trt-2'-dU
Price:
Purity: 97.0%
Stocking Period: 10 Day
Contact: Yang

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Uridine,2'-deoxy-5'-O-(triphenylmethyl)- (9CI)
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

14270-73-6

14270-73-6 structure

Name: 5'-Trt-2'-dU
Chemical Name: 5'-O-Trityl-2'-deoxyuridine
CAS Number: 14270-73-6
Molecular Formula: C₂₈H₂₆N₂O₅
Molecular Weight: 470.52
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-12-22 12:30:01
Modify Date: 2024-01-17 15:19:48
5’-O-Triphenylmethyl-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	5'-O-Trityl-2'-deoxyuridine
Synonyms	1-[(2R,4S,5R)-4-hydroxy-5-(trityloxymethyl)oxolan-2-yl]pyrimidine-2,4-dione 5'-Trt-2'-dU

Description	5’-O-Triphenylmethyl-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	1.3g/cm3
Melting Point	204-205 °C
Molecular Formula	C₂₈H₂₆N₂O₅
Molecular Weight	470.52
Exact Mass	470.18400
PSA	93.55000
LogP	3.19370
Index of Refraction	1.63

HS Code	2934999090

951-78-0

76-83-5

~97%

14270-73-6

Literature: Nguyen, Corinne; Kasinathan, Ganasan; Leal-Cortijo, Isabel; Musso-Buendia, Alexander; Kaiser, Marcel; Brun, Reto; Ruiz-Perez, Luis M.; Johansson, Nils G.; Gonzalez-Pacanowska, Dolores; Gilbert, Ian H. Journal of Medicinal Chemistry, 2005 , vol. 48, # 19 p. 5942 - 5954

951-78-0

14470-28-1

~96%

14270-73-6

Literature: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) Patent: EP1674104 A1, 2006 ; Location in patent: Page/Page column 11; 19 ;

951-78-0

76-83-5

~39%

1140622-58-7

14270-73-6

Literature: Chatelain, Gregory; Debing, Yannick; De Burghgraeve, Tine; Zmurko, Joanna; Saudi, Milind; Rozenski, Jef; Neyts, Johan; Van Aerschot, Arthur European Journal of Medicinal Chemistry, 2013 , vol. 65, p. 249 - 255

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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