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  • Product Name: Sucralose
  • Price: ¥Inquiry/5mg
  • Purity: 98.0%
  • Stocking Period: 10 Day
  • Contact: Xueping-Zheng



56038-13-2

56038-13-2 structure
56038-13-2 structure
  • Name: Sucralose
  • Chemical Name: sucralose
  • CAS Number: 56038-13-2
  • Molecular Formula: C12H19Cl3O8
  • Molecular Weight: 397.634
  • Catalog: Biochemical Carbohydrate Double sugar
  • Create Date: 2018-02-05 08:00:00
  • Modify Date: 2024-01-02 09:19:35
  • Sucralose is an intense organochlorine artificial sweetener.

Name sucralose
Synonyms (2R,3R,4R,5R,6R)-2-{[(2R,3S,4S,5S)-2,5-Bis(chloromethyl)-3,4-dihydroxytetrahydro-2-furanyl]oxy}-5-chloro-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4-diol
1',4,6'-Trichlorogalactosucrose
1,6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl 4-chloro-4-deoxy-α-D-galactopyranoside
a-D-galactopyranoside, 1,6-dichloro-1,6-dideoxy-b-D-fructofuranosyl 4-chloro-4-deoxy-
trichlorosucrose
(2R,3R,4R,5R,6R)-2-[(2R,3S,4S,5S)-2,5-bis(chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-5-chloro-6-(hydroxymethyl)oxane-3,4-diol
MFCD03648615
1,6-dichloro-1,6-dideoxy-b-D-fructofuranosyl 4-chloro-4-deoxy-a-D-galactopyranoside
Sucralose
EINECS 259-952-2
1,6-Dichlor-1,6-dideoxy-β-D-fructofuranosyl-4-chlor-4-deoxy-α-D-galactopyranoside
4,1',6'-Trichloro-4,1',6'-trideoxygalacto-sucrose
1,6-Dichloro-1,6-dideoxy-b-D-fructofuranosyl-4-chloro-4-deoxy-a-D-galactopyranoside
splenda
α-D-Galactopyranoside, 1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl 4-chloro-4-deoxy-
UNII-96K6UQ3ZD4
Description Sucralose is an intense organochlorine artificial sweetener.
Related Catalog
In Vivo The results show that Sucralose induces significant increased incidence of all hematopoietic neoplasias in male mice exposed to 2,000 (p≤0.01), and 16,000 ppm (p≤0.01), with a significant dose-related relationship (p≤0.01). Microscopically, most of the neoplasias among male mice treated with Sucralose at 2,000 to 16,000 ppm are leukemias involving lungs, liver, spleen, lymph nodes, and bone marrow with diffuse permeation of vessels and extensive infiltration of adjacent tissues[1].
Animal Admin Sucralose is pulverized in a standard pelleted diet at concentrations 0, 500, 2,000, 8,000, and 16,000 ppm and is administered to five groups of male (n=117, 114, 90, 66, and 70, respectively) and five groups female (n=102, 105, 60, 65, and 64, respectively) Swiss mice from the 12th day of fetal life until death[1].
References

[1]. M S, et al. Sucralose administered in feed, beginning prenatally through lifespan, induces hematopoietic neoplasias in male swiss mice. Int J Occup Environ Health. 2016 Jan;22(1):7-17.

Density 1.7±0.1 g/cm3
Boiling Point 669.4±55.0 °C at 760 mmHg
Melting Point 125.5ºC
Molecular Formula C12H19Cl3O8
Molecular Weight 397.634
Flash Point 358.7±31.5 °C
Exact Mass 396.014557
PSA 128.84000
LogP 0.68
Vapour Pressure 0.0±4.6 mmHg at 25°C
Index of Refraction 1.604
Storage condition Hygroscopic, -20°C Freezer, Under Inert Atmosphere

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LW5440140
CHEMICAL NAME :
alpha-D-Galactopyranoside, 1,6-dichloro-1,6-dideoxy-beta-D-fructofuranosyl 4-chloro-4-deoxy-
CAS REGISTRY NUMBER :
56038-13-2
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H19-Cl3-O8

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>16 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TBSCDB Trends in Biochemical Sciences. (Elsevier Science Publishing Co., Inc., 655 Avenue of the Americas, New York, NY 10010) V.1- 1976- Volume(issue)/page/year: 3,61,1978
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26-37/39
RIDADR NONH for all modes of transport
RTECS LW5440140
HS Code 2932999099

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Literature: Wu, Jun Jing; Wu, Guang Li; Cai, Qing Hai; Xinyu, Shou; Li, Zi Wen; Liu, Shang; Wang, Man Tang Patent: US2008/58508 A1, 2008 ; Location in patent: Page/Page column 3 ;

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Literature: EMCURE PHARMACEUTICALS LIMITED Patent: WO2007/96726 A2, 2007 ; Location in patent: Page/Page column 32 ;

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Literature: TATE and LYLE TECHNOLOGY LIMITED; WILEY, James, Edwin; JABER, Mohamad, R. Patent: WO2010/151489 A1, 2010 ; Location in patent: Page/Page column 14 ;

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Literature: PHARMED MEDICARE PVT. LTD. Patent: US2009/118493 A1, 2009 ; Location in patent: Page/Page column 3 ;

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Literature: US2010/56773 A1, ; Page/Page column 2 ;

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Literature: US2010/160625 A1, ; Page/Page column 2 ;

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Detail
Literature: EP260979 B1, ;

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Literature: US2011/64812 A1, ;
HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%