Biotin-PEG4-Amide-C6-Azide

Modify Date: 2024-01-10 17:27:39

Biotin-PEG4-Amide-C6-Azide Structure
Biotin-PEG4-Amide-C6-Azide structure
Common Name Biotin-PEG4-Amide-C6-Azide
CAS Number 1006592-62-6 Molecular Weight 615.79
Density N/A Boiling Point N/A
Molecular Formula C27H49N7O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotin-PEG4-Amide-C6-Azide


Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Biotin-PEG4-Amide-C6-Azide

 Biotin-PEG4-Amide-C6-Azide Biological Activity

Description Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C27H49N7O7S
Molecular Weight 615.79