Biotin-PEG4-Picolyl azide

Modify Date: 2024-01-10 20:33:21

Biotin-PEG4-Picolyl azide Structure
Biotin-PEG4-Picolyl azide structure
Common Name Biotin-PEG4-Picolyl azide
CAS Number 2222687-71-8 Molecular Weight 622.74
Density N/A Boiling Point N/A
Molecular Formula C27H42N8O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotin-PEG4-Picolyl azide


Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Biotin-PEG4-Picolyl azide

 Biotin-PEG4-Picolyl azide Biological Activity

Description Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C27H42N8O7S
Molecular Weight 622.74