PSB 0788
Modify Date: 2024-01-09 08:31:23
PSB 0788 structure
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Common Name | PSB 0788 | ||
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| CAS Number | 1027513-54-7 | Molecular Weight | 543.03800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H27ClN6O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PSB 0788PSB-0788 (compound 17), xanthine-8-yl-benzenesulfonamide derivative, is a new selective high-affinity A2B antagonist with IC50 value of 3.64 nM and Ki value of 0.393 nM, respeactively. PSB-0788 (compound 17) can be used for the research for chronic inflammatory lung diseases[1]. |
| Name | 8-(4-(4-(4-chlorobenzyl)piperazine-1-sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione |
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| Synonym | More Synonyms |
| Description | PSB-0788 (compound 17), xanthine-8-yl-benzenesulfonamide derivative, is a new selective high-affinity A2B antagonist with IC50 value of 3.64 nM and Ki value of 0.393 nM, respeactively. PSB-0788 (compound 17) can be used for the research for chronic inflammatory lung diseases[1]. |
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| Related Catalog | |
| Target |
IC50: 3.64 nM (A2BAdoR); Ki: 0.393 nM (human, A2B); >1000 nM ( A3 human recombinant); 333 nM ( A2A human recombinant); 1730 nM ( A2A rat brain striatal membranes); 2240 nM ( A1 human recombinant); 386 nM ( A1 rat brain cortical membranes))[1].[1] |
| In Vitro | PSB-0788 (compound 17) has high potency at the A2BAdoR with IC50 value of 3.64 nM. PSB-0788 (compound 17) has good profile of affinity and selectivity (Ki: 0.393 nM ( A2B human recombinant); >1000 nM ( A3 human recombinant); 333 nM ( A2A human recombinant); 1730 nM ( A2A rat brain striatal membranes); 2240 nM ( A1 human recombinant); 386 nM ( A1 rat brain cortical membranes))[1]. |
| References |
| Molecular Formula | C25H27ClN6O4S |
|---|---|
| Molecular Weight | 543.03800 |
| Exact Mass | 542.15000 |
| PSA | 132.54000 |
| LogP | 3.60640 |
| 5-Nonyloxytryptamine oxalate |