Propargyl-PEG1-THP

Modify Date: 2024-01-09 20:46:36

Propargyl-PEG1-THP Structure
Propargyl-PEG1-THP structure
Common Name Propargyl-PEG1-THP
CAS Number 119096-95-6 Molecular Weight 184.23
Density N/A Boiling Point N/A
Molecular Formula C10H16O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-PEG1-THP


Propargyl-PEG1-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG1-THP

 Propargyl-PEG1-THP Biological Activity

Description Propargyl-PEG1-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H16O3
Molecular Weight 184.23