Propargyl-PEG1-NH2

Modify Date: 2024-01-03 13:06:16

Propargyl-PEG1-NH2 Structure
Propargyl-PEG1-NH2 structure
Common Name Propargyl-PEG1-NH2
CAS Number 122116-12-5 Molecular Weight 99.13110
Density N/A Boiling Point N/A
Molecular Formula C5H9NO Melting Point N/A
MSDS N/A Flash Point 50 °C

 Use of Propargyl-PEG1-NH2


Propargyl-PEG1-NH2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name (2-Propargyloxyethyl)amine

 Propargyl-PEG1-NH2 Biological Activity

Description Propargyl-PEG1-NH2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C5H9NO
Molecular Weight 99.13110
Flash Point 50 °C
Exact Mass 99.06840
PSA 35.25000
LogP 0.29520
Index of Refraction 1.45

 Precursor & DownStream

Precursor  0

DownStream  1

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