NHS-PEG4-SPDP
Modify Date: 2024-01-10 07:12:56
NHS-PEG4-SPDP structure
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Common Name | NHS-PEG4-SPDP | ||
|---|---|---|---|---|
| CAS Number | 1334177-95-5 | Molecular Weight | 559.653 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C23H33N3O9S2 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of NHS-PEG4-SPDPSPDP-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | N-{15-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}-3-(2-pyridinyldisulfanyl)propanamide |
|---|---|
| Synonym | More Synonyms |
| Description | SPDP-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C23H33N3O9S2 |
| Molecular Weight | 559.653 |
| Exact Mass | 559.165833 |
| LogP | -0.89 |
| Index of Refraction | 1.579 |
| Storage condition | -20°C |
| N-{15-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}-3-(2-pyridinyldisulfanyl)propanamide |
| Propanamide, N-[15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]-3-(2-pyridinyldithio)- |