Tos-PEG9-Boc

Modify Date: 2024-01-10 11:04:28

Tos-PEG9-Boc Structure
Tos-PEG9-Boc structure
Common Name Tos-PEG9-Boc
CAS Number 1345337-28-1 Molecular Weight 652.791
Density 1.1±0.1 g/cm3 Boiling Point 677.8±55.0 °C at 760 mmHg
Molecular Formula C30H52O13S Melting Point N/A
MSDS N/A Flash Point 363.7±31.5 °C

 Use of Tos-PEG9-Boc


Tos-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-Methyl-2-propanyl 1-{[(4-methylphenyl)sulfonyl]oxy}-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate
Synonym More Synonyms

 Tos-PEG9-Boc Biological Activity

Description Tos-PEG9-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 677.8±55.0 °C at 760 mmHg
Molecular Formula C30H52O13S
Molecular Weight 652.791
Flash Point 363.7±31.5 °C
Exact Mass 652.312866
LogP 0.30
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.487

 Synonyms

2-Methyl-2-propanyl 1-{[(4-methylphenyl)sulfonyl]oxy}-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate
3,6,9,12,15,18,21,24-Octaoxaheptacosan-27-oic acid, 1-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester
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