Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Tos-PEG2-Boc
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: Tos-PEG2-t-butyl ester
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Tos-PEG2-t-butyl ester
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

1309666-78-1

1309666-78-1 structure

1309666-78-1 structure

Name: Tos-PEG2-Boc
Chemical Name: Tos-PEG2-t-butyl ester
CAS Number: 1309666-78-1
Molecular Formula: C₁₆H₂₄O₆S
Molecular Weight: 344.423
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-11-30 10:50:37
Modify Date: 2024-01-10 11:56:27
Tos-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Tos-PEG2-t-butyl ester
Synonyms	Propanoic acid, 3-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]-, 1,1-dimethylethyl ester MFCD22201525 2-Methyl-2-propanyl 3-(2-{[(4-methylphenyl)sulfonyl]oxy}ethoxy)propanoate

Description	Tos-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.

Density	1.2±0.1 g/cm3
Boiling Point	460.6±30.0 °C at 760 mmHg
Molecular Formula	C₁₆H₂₄O₆S
Molecular Weight	344.423
Flash Point	232.3±24.6 °C
Exact Mass	344.129364
LogP	2.81
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.501

Hazard Codes	Xi