1807537-35-4
1807537-35-4 structure
- Name: Tos-PEG2-CH2COOH
- Chemical Name: Tos-PEG3-CH2CO2H
- CAS Number: 1807537-35-4
- Molecular Formula: C13H18O7S
- Molecular Weight: 318.343
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-04 07:39:15
- Modify Date: 2024-01-15 10:47:13
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Tos-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Tos-PEG3-CH2CO2H |
|---|---|
| Synonyms |
[2-(2-{[(4-Methylphenyl)sulfonyl]oxy}ethoxy)ethoxy]acetic acid
MFCD27977495 Acetic acid, 2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]- |
| Description | Tos-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 512.8±40.0 °C at 760 mmHg |
| Molecular Formula | C13H18O7S |
| Molecular Weight | 318.343 |
| Flash Point | 263.9±27.3 °C |
| Exact Mass | 318.077332 |
| LogP | 0.37 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.526 |