Tos-PEG9-Tos

Modify Date: 2024-01-02 17:43:11

Tos-PEG9-Tos Structure
Tos-PEG9-Tos structure
Common Name Tos-PEG9-Tos
CAS Number 109635-64-5 Molecular Weight 722.86100
Density N/A Boiling Point N/A
Molecular Formula C32H50O14S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tos-PEG9-Tos


Tos-PEG9-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Nonaethylene glycol ditosylate

 Tos-PEG9-Tos Biological Activity

Description Tos-PEG9-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C32H50O14S2
Molecular Weight 722.86100
Exact Mass 722.26400
PSA 177.34000
LogP 4.70860
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