Tos-PEG8-Tos
Modify Date: 2024-01-09 22:15:08
Tos-PEG8-Tos structure
|
Common Name | Tos-PEG8-Tos | ||
|---|---|---|---|---|
| CAS Number | 57436-38-1 | Molecular Weight | 678.80800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C30H46O13S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Tos-PEG8-TosTos-PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 2-[2-[2-[2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate |
|---|---|
| Synonym | More Synonyms |
| Description | Tos-PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C30H46O13S2 |
|---|---|
| Molecular Weight | 678.80800 |
| Exact Mass | 678.23800 |
| PSA | 168.11000 |
| LogP | 4.69200 |
|
~99%
Tos-PEG8-Tos CAS#:57436-38-1 |
| Literature: Chen, Yiyan; Baker, Gregory L. Journal of Organic Chemistry, 1999 , vol. 64, # 18 p. 6870 - 6873 |
|
~%
Tos-PEG8-Tos CAS#:57436-38-1 |
| Literature: Chen, Yiyan; Baker, Gregory L. Journal of Organic Chemistry, 1999 , vol. 64, # 18 p. 6870 - 6873 |
|
~%
Tos-PEG8-Tos CAS#:57436-38-1 |
| Literature: Chen, Yiyan; Baker, Gregory L. Journal of Organic Chemistry, 1999 , vol. 64, # 18 p. 6870 - 6873 |
|
~%
Tos-PEG8-Tos CAS#:57436-38-1 |
| Literature: Chen, Yiyan; Baker, Gregory L. Journal of Organic Chemistry, 1999 , vol. 64, # 18 p. 6870 - 6873 |
CAS#:6790-09-6| 1,24-bis(tosyloxy)-3,6,9,12,15,18,21-heptaoxatetracosane |
| Octaethylene glycol di(p-toluenesulfonate) |
| Octaethylene glycol ditosylate |
| 3,6,9,12,15,18,21-Heptaoxatricosane-1,23-diyl bis(4-methylbenzenesulfonate) |
| 1,23-bis(tosyloxy)-3,6,9,12,15,18,21-heptaoxatricosane |