THP-PEG8-Tos

Modify Date: 2024-01-13 20:49:34

THP-PEG8-Tos Structure
THP-PEG8-Tos structure
Common Name THP-PEG8-Tos
CAS Number 669556-37-0 Molecular Weight 520.63300
Density N/A Boiling Point N/A
Molecular Formula C24H40O10S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of THP-PEG8-Tos


THP-PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 17-(tetrahydro-2H-pyran-2-yloxy)-3,6,9,12,15-pentaoxaheptadecyl 4-methylbenzenesulfonate
Synonym More Synonyms

 THP-PEG8-Tos Biological Activity

Description THP-PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C24H40O10S
Molecular Weight 520.63300
Exact Mass 520.23400
PSA 116.36000
LogP 3.40730

 Synonyms

17-[(tetrahydro-2H-pyran-2-yl)oxy]-1-tosyloxy-3,6,9,12,15-pentaoxaheptadecane
1-(2H-tetrahydropyran-2-yloxy)-17-tosyloxy-3,6,9,12,15-pentaoxaheptadecane
Top Suppliers:I want be here



Get all suppliers and price by the below link:

THP-PEG8-Tos suppliers

THP-PEG8-Tos price