PEG9-Tos

Modify Date: 2024-01-12 19:32:28

PEG9-Tos Structure
PEG9-Tos structure
Common Name PEG9-Tos
CAS Number 886469-23-4 Molecular Weight 524.622
Density 1.2±0.1 g/cm3 Boiling Point 615.0±55.0 °C at 760 mmHg
Molecular Formula C23H40O11S Melting Point N/A
MSDS N/A Flash Point 325.8±31.5 °C

 Use of PEG9-Tos


PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name PEG8-Ts
Synonym More Synonyms

 PEG9-Tos Biological Activity

Description PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 615.0±55.0 °C at 760 mmHg
Molecular Formula C23H40O11S
Molecular Weight 524.622
Flash Point 325.8±31.5 °C
Exact Mass 524.229126
LogP -1.56
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.497

 Synonyms

23-Hydroxy-3,6,9,12,15,18,21-heptaoxatricos-1-yl 4-methylbenzenesulfonate
PEG8-Ts
3,6,9,12,15,18,21-Heptaoxatricosane-1,23-diol, mono(4-methylbenzenesulfonate)
PEG8-OTs
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