Mutant IDH1-IN-1

Modify Date: 2024-01-02 05:12:16

Mutant IDH1-IN-1 structure	Common Name	Mutant IDH1-IN-1
	CAS Number	1355326-21-4	Molecular Weight	498.591
	Density	1.2±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₃₀H₃₁FN₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Mutant IDH1-IN-1

Mutant IDH1-IN-1 is a mutant-selective IDH1 inhibitor with with IC50s of 4, 42, 80 and 143 nM against mutant IDH1 R132C/R132C, IDH1 R132H/R132H, IDH1 R132H/WT and wild type IDH1, respectively.

Name	2-(1H-Benzimidazol-1-yl)-N-[2-(cyclohexylamino)-1-(2-methylphenyl)-2-oxoethyl]-N-(3-fluorophenyl)acetamide
Synonym	More Synonyms

Description	Mutant IDH1-IN-1 is a mutant-selective IDH1 inhibitor with with IC50s of 4, 42, 80 and 143 nM against mutant IDH1 R132C/R132C, IDH1 R132H/R132H, IDH1 R132H/WT and wild type IDH1, respectively.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Isocitrate Dehydrogenase (IDH) Research Areas >> Cancer
Target	IC50: 4 nM (IDH1 R132C/R132C), 42 nM (IDH1 R132H/R132H), 80 nM (IDH1 R132H/WT), 143 nM (IDH1 wild type)[1]
References	[1]. Deng G, et al. Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule. J Biol Chem. 2015 Jan 9;290(2):762-74.

Density	1.2±0.1 g/cm3
Molecular Formula	C₃₀H₃₁FN₄O₂
Molecular Weight	498.591
Exact Mass	498.243103
LogP	5.62
Index of Refraction	1.637
Storage condition	2-8℃

2-(1H-Benzimidazol-1-yl)-N-[2-(cyclohexylamino)-1-(2-methylphenyl)-2-oxoethyl]-N-(3-fluorophenyl)acetamide

1H-Benzimidazole-1-acetamide, N-[2-(cyclohexylamino)-1-(2-methylphenyl)-2-oxoethyl]-N-(3-fluorophenyl)-

Mutant IDH1-IN-1

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: MutantIDH1-IN-1
Price: Negotiable
Purity: 99.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Mutant IDH1-IN-1
Price: $560.0/100mg $1100.0/250mg $2000.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Mutant IDH1-IN-1
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Mutant IDH1-IN-1
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Mutant IDH1-IN-1 suppliers

Price: $462/10mM*1mLinDMSO

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