PF-06651481-00

Modify Date: 2024-01-10 00:00:27

PF-06651481-00 Structure
PF-06651481-00 structure
Common Name PF-06651481-00
CAS Number 1391063-17-4 Molecular Weight 530.45
Density N/A Boiling Point N/A
Molecular Formula C26H29Cl2N5O3 Melting Point N/A
MSDS USA Flash Point N/A

 Use of PF-06651481-00


Bosutinib isomer is a ligand or inhibitor with high binding affinity for both Wee1 and Wee2, with Kd values of 43.7 ± 10.0 and 4.7 ± 2.3 nM, respectively[1].

 Names

Name bosutinib-I
Synonym More Synonyms

 PF-06651481-00 Biological Activity

Description Bosutinib isomer is a ligand or inhibitor with high binding affinity for both Wee1 and Wee2, with Kd values of 43.7 ± 10.0 and 4.7 ± 2.3 nM, respectively[1].
Related Catalog
References

[1]. Zhu JY, et al. Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors. J Med Chem. 2017 Sep 28;60(18):7863-7875.  

 Chemical & Physical Properties

Molecular Formula C26H29Cl2N5O3
Molecular Weight 530.45
Exact Mass 529.16500
PSA 82.88000
LogP 5.13918

 Safety Information

RIDADR NONH for all modes of transport

 Synonyms

Bosutinib Isomer 1
bosutinib