Shanghai Nianxing Industrial Co., Ltd
China
Product Name: PF-06651481-00
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: PF-06651481-00
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

1391063-17-4

1391063-17-4 structure

1391063-17-4 structure

Name: PF-06651481-00
Chemical Name: bosutinib-I
CAS Number: 1391063-17-4
Molecular Formula: C₂₆H₂₉Cl₂N₅O₃
Molecular Weight: 530.45
Catalog: Signaling Pathways Cell Cycle/DNA Damage Wee1
Create Date: 2016-12-17 16:25:10
Modify Date: 2024-01-10 00:00:27
Bosutinib isomer is a ligand or inhibitor with high binding affinity for both Wee1 and Wee2, with Kd values of 43.7 ± 10.0 and 4.7 ± 2.3 nM, respectively[1].

Name	bosutinib-I
Synonyms	Bosutinib Isomer 1 bosutinib

Description	Bosutinib isomer is a ligand or inhibitor with high binding affinity for both Wee1 and Wee2, with Kd values of 43.7 ± 10.0 and 4.7 ± 2.3 nM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Wee1
References	[1]. Zhu JY, et al. Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors. J Med Chem. 2017 Sep 28;60(18):7863-7875.

Molecular Formula	C₂₆H₂₉Cl₂N₅O₃
Molecular Weight	530.45
Exact Mass	529.16500
PSA	82.88000
LogP	5.13918

RIDADR	NONH for all modes of transport