Chloro-PEG2-Boc

Modify Date: 2024-01-16 19:26:06

Chloro-PEG2-Boc Structure
Chloro-PEG2-Boc structure
Common Name Chloro-PEG2-Boc
CAS Number 1442085-43-9 Molecular Weight 238.71
Density N/A Boiling Point N/A
Molecular Formula C10H19ClO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Chloro-PEG2-Boc


Chloro-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Chloro-PEG2-Boc
Synonym More Synonyms

 Chloro-PEG2-Boc Biological Activity

Description Chloro-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H19ClO4
Molecular Weight 238.71

 Synonyms

MFCD31693523